Wednesday, October 13, 2010

Testosterone may help women with heart failure

Cardiologist Dr. Justin Ezekowitz, an assistant professor at the University of Alberta in Canada. "We have a hit a wall in terms of what we can do for patients with heart failure. We've made a lot of progress, but there are still patients who have symptoms despite the premium blend of medications and fancy devices."

Heart failure is most common in people who are in their 60s, 70s and beyond. Their hearts fail to pump blood properly due to factors such as previous heart attacks or high blood pressure, Ezekowitz said. The patients are often out of breath and become extremely tired, he said. "This is tiredness where they're completely out of gas even after walking a block."

Researchers have previously linked testosterone to better health in elderly men with heart failure. In the new study, researchers randomly assigned 36 women with heart failure to receive normal medical treatment by itself or with skin patches that administered testosterone to their bodies. The results appear in the Oct. 12 issue of the online Journal of the American College of Cardiology.

The researchers found that testosterone improved the women's tolerance for exercise and boosted their muscle strength, said study author Dr. Ferdinando Iellamo, a researcher at the University of Rome Tor Vergata in Italy. All of these factors "play a role in determining the prognosis and survival of female patients with chronic heart failure," Iellamo said.

1 comment:

  1. A new testosterone study from Bhasin in NEJM was halted early because the testosterone treated group had more heart attacks. A closer look reveals a flawed study with a skewed test group of obese, immobilized elderly men with heart disease. 75% were heavy smokers. Almost all had hypertension. Many were diabetics, 60% were on statin drugs and average age was 74.

    The Bhasin study is refuted by decades of previous studies showing that testosterone is beneficial for the heart. Three population studies have shown that low testosterone levels in men are associated with increased mortality from cardiovascular disease. A recent study by Chris Malkin in Heart followed 900 men with angiographic demonstration of coronary artery disease over 8 years. The men with low testosterone had 22% mortality compared to only 12 % for men with normal testosterone levels. Testosterone reduces time to cardiac ischemia in men stable angina and improves functional capacity in men with heart failure. Similarly, testosterone is beneficial for women with heart failure, as well.

    For more:

    http://jeffreydach.com/2010/10/14/testosterone-causes-heart-attacks-by-jeffrey-dach-md.aspx

    jeffrey dach md

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