$1,000 dollar genome by 2012

By 2012, sequencing the human genome will be done in two hours and will cost $1,000, Ion Torrent’s Jonathan Rothberg said at a recent conference.

As companies race to crack the $1,000 genome, contending DNA machines in the marketplace suggest an end is near.

Ion Torrent’s DNA machine reads sequences based on chemicals and electronic technology.

The technology is called the Personal Genome Machine and it has been used to determine the source of E. coli or mutations present in the genomes of patients’ cancers.

The Ion Personal Genome Machine, which is about the size of a desktop computer, uses chemistry and semiconductor technology to produce readouts of genetic information in a couple of hours.

Christopher Mims wrote in Technology Review:

“Right now don’t have very many correlations between those 3 billion base pairs [of the human genome] and outcomes or medicines,” says Rothberg.

He predicts it will take at least 10 years of clinical experiments with full genome sequencing to get us to the point where we can begin to unlock its value.

“And it will be 20 years before we understand cancer at same level as HIV and can come up with combinations of medicine [tailored] for each individual,” says Rothberg.